Creatinine measurement is a blood test, which mainly reflects the kidney function. The substance creatinine is a product of muscle metabolism, and the muscles mentioned here are own muscles as well as lean muscle from exogenous intake. This substance is filtered by the kidneys, but not reabsorbed or secreted by the renal tubules, so it is a very good indicator of kidney function and is relatively more accurate than urea, which is easily influenced by diet and renal perfusion. When creatinine rises, it indicates kidney failure, which is more serious and may develop into uremia if treatment is not timely. Therefore, as soon as creatinine is found to be elevated, we must actively search for the cause and treat it from the underlying cause. Some people will also find creatinine lower, creatinine lower clinical significance is not very big, generally and patients with too strict dietary control and body thin, muscle content is very big relationship, it is recommended that you can eat more lean meat, participate in more weight-bearing exercise to increase the body’s muscle content.