Why is urine protein high despite normal creatinine?

Normal creatinine indicates that the kidney function is still normal, but high urine protein indicates that there have been kidney-related diseases, which is very common in clinical practice, because the early stage of many kidney diseases only shows abnormal urine tests, which can show an increase in urine protein, but there is no damage to kidney function, for example, in the early stage of glomerulonephritis and nephrotic syndrome are positive for urine protein. And the kidney function is completely normal, only when the kidney disease progresses to a certain degree, will there be an increase in creatinine. It is necessary to assess the specific condition as well as to clarify the cause, and further clarify the diagnosis by checking the 24-hour urine protein quantification, kidney puncture biopsy and other related items for targeted treatment.