If a woman has headache and eye pain during her menstrual period, she may have a migraine. Migraines are caused by a variety of factors. During menstruation, the vasculature of the brain is unable to adapt to the sudden change in endocrine hormones due to the sudden drop in estrogen in the body, and the contraction and diastole of the blood vessels become impaired. Patients are advised to take oral medication to prevent migraine attacks during the first week before menstruation, for example, one tablet of the calcium antagonist nimodipine a day or one tablet of Betaloc 12.5mg a day to prevent migraine attacks.