Anti-inflammatory drugs generally refer to antibiotics. Closed fractures generally do not require anti-inflammatory drugs. If there is an open injury, oral amoxicillin and cefadroxil can be taken to prevent infection, and intravenous fluids are required if necessary. A fracture is a break in the continuity of the bone, and there are closed fractures and open fractures. There is no wound in closed fracture, and there is localized swelling and pain after fracture, the possibility of infection in this kind of fracture is very small, and anti-inflammatory drugs are usually not needed. If it is open fracture, there is contamination at the fracture can apply antibiotics according to the fracture, such as cephalosporin antibiotics and penicillins, etc. Serious cases also need to consider intravenous infusion, if necessary, according to the results of bacterial culture and drug sensitivity test to select sensitive antibiotics. Therefore, whether the fracture needs to apply anti-inflammatory drugs is decided according to the type of fracture, and sensitive drugs are applied for different injuries under the guidance of doctors.