Can pituitary microadenoma be left untreated?

If pituitary microadenoma does not secrete hormones abnormally, does not affect normal pituitary function, and does not compress the surrounding vascular nerves, it can be closely observed for a long time and reviewed regularly, and no treatment is needed. However, if it is a functional pituitary adenoma that causes abnormal secretion of certain hormones, such as lactogen, growth hormone, adrenocorticotropic hormone and thyrotropic hormone, and results in symptoms and signs such as amenorrhea, breast overflow, infertility, acromegaly, centripetal obesity, purple skin lines, hypertension and hyperglycemia, and affects the health of the patient, then surgery is necessary.