Nondepressed mucous edema is the characteristic clinical response to thyroid hormone deficiency in adults. Primary hypothyroidism (hypothyroidism) is the most common type and is probably an autoimmune disease. It usually occurs as a result of Hashimoto’s thyroiditis and is often accompanied by a firm goiter, after which, as the disease progresses, a shrunken fibrous thyroid gland with no or little function develops. The second common type is post-treatment hypothyroidism, especially due to hyperthyroidism undergoing radioactive iodine and surgical treatment, propylthiouracil, tabazole and iodine over-treatment of hypothyroidism, which often recovers after termination of the treatment, and mild hypothyroidism is common in older women. So what is the differential diagnosis of non-depressed mucous edema? Here’s what you need to know. The main thing is to differentiate with depressed edema Depressed edema: when there is excessive accumulation of body fluids in the subcutaneous tissue interstitial space, the skin is pale, swollen, the wrinkles become shallow, the local temperature is low, the elasticity is poor, press the local (such as the inner ankle, tibialis anterior area, or frontal and zygomatic areas) skin with the finger, if there is a depression, it is known as depressed edema (pitting edema) or dominant water (frank edema). The depression may take a few seconds to a minute to settle after the finger is released. This is due to the pitting edema, subcutaneous tissue interstitial more free water, due to press the local pressure increases, so that the free water to the lower pressure, so there is a depression, finger release, free water back to the original time that is the time for the depression to calm down.