The bottom of the toes long hard pimples mainly consider and callus, metatarsal warts, corns and so on. 1. callus: because of the foot toes long-term friction, extrusion and the formation of keratin hyperplasia rash, manifested in the bottom of the toes long hard pimples of the phenomenon, commonly known as the callus, more than no harm. 2. metatarsal warts: with the infection of human papillomavirus, virus stimulation of the bottom of the toes can cause local epidermal hyperplasia, and gradually develop into metatarsal warts hardened damage, manifested in the bottom of the toes long hard pimples, contagious, lesions of varying sizes, accompanied by tenderness. 3. corns: the bottom of the toes for a long time by extrusion or friction and lead to local keratin hyperplasia, the formation of yellowish or dark yellow conical corns, the boundary is clear, can be manifested in the bottom of the toes with hard pimples of the symptom, walking or standing, the local pressure can appear obvious pain. Hard bumps on the bottom of the toes can also be caused by other reasons, if there is pain and other symptoms, it is recommended to consult a doctor in a timely manner, clear the cause of the active treatment, so as not to delay the condition.