High pressure 130mmHg low pressure 64mmHg is the increase of pulse pressure difference, usually because of the decrease of blood vessel elasticity, which can be alleviated and prevented by adjusting lifestyle, controlling blood pressure and actively treating the original disease. 1. Lifestyle adjustment: Smoking and drinking will lead to abnormal constriction of arterial blood vessels, resulting in increased pulse pressure difference. Therefore, patients need to quit smoking and drinking, and maintain a low-salt and low-fat diet to reduce the causes of abnormal vasoconstriction. 2. The common treatment for increased pulse pressure is to control the blood pressure as a whole, especially for the elderly with decreased elasticity of the blood vessel wall, to take antihypertensive drugs under the guidance of the doctor on time, and to monitor the blood pressure on a daily basis. 3. Increased pulse pressure difference may be related to aortic sclerosis lesions, rheumatic heart disease or hyperthyroidism and other diseases, it is recommended to go to the hospital to systematically identify the cause of the disease, for the treatment of the original disease. When the patient has a high pressure of 130mmHg and low pressure of 64mmHg, and the difference between the repeated measurements is not large, it is necessary to actively seek medical treatment, so as to achieve early detection, early diagnosis and early treatment, and pay attention to the symptom, so as to avoid delaying the condition.