Itchy soles of the feet and palms, consider the following possibilities: 1. It may be hives. It can appear as a patchy erythematous or wind-blown rash on the soles of the feet and palms, and the rash can expand after scratching, accompanied by a more pronounced itching sensation. You can take Avastin capsules orally 3 times a day, 1 capsule each time, and treat it with topical application of Furamax lotion. The main cause is allergy, due to excessive consumption of beef, mutton, seafood, chicken, duck, goose, dog meat, and hair products such as eggs and milk, and also due to excessive consumption of spicy and irritating foods, including raw onion, raw garlic, chili pepper, etc. 2. Eczema may also be caused by the above-mentioned allergies, with flaky erythema, densely distributed papules on the soles of the feet and hands, and some of the papules forming patches. 3. Fungal infections caused by It is more likely to be tinea cruris and tinea pedis, which can appear as fine papules and fine scales with itching, and can be treated with topical terbinafine hydrochloride gel.