There may be the following reasons for low back pain at night: first, tumor, when the lumbar vertebral body or annex has tumor or metastatic tumor, there can be low back pain at night, which is a pain characteristic of tumor, and it is the resting pain when sleeping, then we should carry out nuclear magnetic and CT examination of lumbar spine at an early stage, and if necessary, carry out ECT examination, in order to carry out early diagnosis and early treatment. Secondly, osteoporosis, when the lumbar spine has osteoporosis, the symptom of lumbar pain when sleeping can appear, then we should carry out the blood test as well as lumbar spine X-ray film, CT examination, for early diagnosis and early treatment. Thirdly, severe lumbar muscle strain and lumbar dorsal muscular fasciitis can also occur when sleeping with low back pain, then we should carry out the relevant examination and checkup to exclude other diseases for diagnosis.