A positive antibody IGM for herpes simplex virus type 2 indicates a current herpes simplex virus infection. And many of us consider it to be a primary infection. The main treatment for this disease is some oral topical medications. Topical medications should be used that are astringent, drying, and prevent secondary infections, such as acyclovir cream or penciclovir cream. If there is secondary infection in the lesion area, topical treatment with mupirocin ointment, and compounded polymyxin B. Systemic treatment is mainly acyclovir tablets or, if necessary, an intravenous injection of adenosine. It is important to pay attention to strengthening the resistance, usually more exercise, less drinking and staying up late, etc., to try to avoid the recurrence of herpes simplex virus.