In clinical work, we found that many patients suffering from insomnia are different degrees of worry about the addiction of sedative-hypnotic drugs. Do not know: sedative-hypnotic drug addiction is conditional, not easy to become addicted after use. As long as the rational selection of drugs, sedative-hypnotic drugs are generally not addictive, at the same time, insomnia can also be effectively relieved or cured. How to choose sedative-hypnotic drugs reasonably? What to pay attention to? First, short-term use of medication, the right amount of medication, alternating medication. Continuous use of drugs is generally not more than three or four weeks. The same kind of drug is generally not more than two or three weeks of continuous use. As long as not a large number of continuous use of the same variety of sedative-hypnotic drugs, can be very good to avoid producing tolerance, addiction. Hunan Second People’s Hospital Mental Health Center Liu Guoyang Second, intermittent medication: there is absolutely no need to use seven days of medication per week, you can choose three to five days of evening medication according to the situation. Third, if you need to avoid the next day drowsy “hangover reaction”, reduce the cognitive function and fine motor coordination during the day, you can choose the body clearance fast (medical called half sad period short) of the drug. Such as: zolpidem, zopiclone and so on. Fourth, hypnotic drugs should not be combined with other central inhibitors as much as possible. Pregnant women and people with sleep apnea should not use it. Elderly patients, hepatic and renal function impairment should be used in reduced doses. Fifth, the difficulty in falling asleep or insomnia in the elderly to short-acting hypnotic drugs, such as: zolpidem, zopiclone, zaleplon, etc.. Liver disease or elderly patients often choose lorazepam or oxazepam, because both are the final metabolite of Valium, do not need to be metabolized in the liver. Those who are prone to early awakening can use intermediate-acting sedative-hypnotics, such as alprazolam tablets, eszopiclone tablets, lorazepam and so on. Daytime anxiety is obvious, can consider the use of long-acting sedative-hypnotic drugs, such as clonazepam, diazepam and so on. Six, if you need to stop, it is important to pay attention to the desirability of slow stopping should not stop suddenly. Otherwise, there will be insomnia rebound or withdrawal symptoms. Happily, zolpidem, zopiclone, zaleplon and other new hypnotic drugs are generally better able to avoid these problems. There are also some patients who believe that sedative hypnotics can cause Alzheimer’s disease, neurasthenia or depression. In fact, this is a complete misunderstanding, and medical research has concluded that there is no causal relationship between them at all.