A spider bite can manifest itself as localized redness, swelling, and pain at the site of the bite, and if the wound is large, there may also be localized bleeding, and some patients may also develop allergic manifestations such as macular redness and swelling around the wound, or a wind-blown urticaria, and the rash is mainly itchy and also combined with localized pain. If the local inflammatory or allergic manifestations spread to the whole limb, the whole limb will be red, swollen, hot, painful, and numb. If the toxin invades the whole body through blood circulation, dizziness, headache, nausea, vomiting, and numbness may occur in mild cases, and in severe cases, the state of consciousness may be affected and symptoms such as confusion and shock may occur.