Cornified foci in the lungs are not found in many people, as this is a description of pathology found on imaging that is not found in the normal population. There are many reasons for the appearance of cornified foci in the lungs, such as the more common one is hematogenous disseminated tuberculosis, which is a specific type of tuberculosis. Other inflammatory conditions in the lungs or bronchial tubes can also stimulate the production of cornified foci in the lungs. There are also space-occupying lesions in the lungs, such as bronchopulmonary carcinoma, alveolar cell carcinoma, and metastatic foci in the lungs from malignant tumors outside the lungs. At this time, there will be different clinical manifestations, such as irritating dry cough or coughing, coughing a large amount of purulent sputum, accompanied by hemoptysis, chest tightness, shortness of breath and so on. Clinically, lung CT and sputum can be taken for pathogenetic examination, as well as drug sensitivity test, and biopsy of pulmonary granular foci can also be taken for pathological examination to clarify the cause of the disease.