The possible consequences of untreated choledocholithiasis include: complication of cholangitis and even systemic infection, inducing biliary pancreatitis, causing liver damage, and inducing cholangiocarcinoma and so on. 1. Complicated cholangitis and even systemic infection: when choledocholithiasis stone is embedded, bile drainage is not smooth, and it is easy to complicate biliary tract infection in the bile duct, and acute and chronic cholangitis will occur. When the bile duct is completely blocked, it can cause the pressure in the bile duct to rise, and the infected bile will flow backward into the liver, and enter the systemic circulation through the hepatic circulation, thus inducing systemic infection, which can cause infectious shock or even death in serious cases. 2. Induce biliary pancreatitis: choledocholithiasis with the flow of bile downward, embedded in the duodenal jugular abdomen can cause pancreatic duct blockage, and then trigger the reflux of pancreatic fluid and induce acute and chronic pancreatitis. 3. Causing liver injury: infected bile retrograde into the liver can form infected foci or abscess in the liver, which can seriously damage liver function; long-term bile stasis can also induce cholestatic liver injury or even liver cirrhosis. 4. Induce cholangiocarcinoma: cholangiocarcinoma is a malignant tumor originated from epithelial cells of bile ducts, and some researches show that about 1/3 of cholangiocarcinoma patients are combined with cholangiocarcinoma, and about 5-10% of patients with cholangiocarcinoma will be cancerous, which suggests that cholangiocarcinoma is closely related to cholangiocarcinoma. If not treated in time, bile duct stones will induce a series of complications, which may cause serious organ damage or even endanger life in severe cases. It is suggested that patients should go to the hospital as soon as possible and be treated accordingly under the guidance of professional doctors.