Epilepsy is caused by abnormal synchronous discharges in the cerebral cortex. There are different types of seizures and different ways to deal with them. Some patients have mild epilepsy, i.e., petit mal seizures also known as disoriented seizures, with symptoms such as brief wandering and slamming of the mouth, which can recover on their own within a short time and cause less brain damage. Some patients have grand mal seizures, characterized by sudden loss of consciousness and generalized convulsions, which last longer. If the patient is not in the hospital at the time of seizure, 120 should be called first, followed immediately by giving the patient a flat position with the head to the side, keeping the airway open, placing a towel between the upper and lower teeth to avoid choking and biting the tongue, and not pressing the patient hard during the seizure to avoid fractures. If the seizure persists for more than 5 minutes, it is called persistent status epilepticus, which can lead to irreversible brain damage and must be treated in an emergency center or regular hospital. Some patients are treated with phenytoin sodium as the first choice for grand mal seizures in the hospital. If the seizure is persistent, diazepam is applied, which is an immediate slow intravenous push of diazepam. Midazolam maleate or propofol with liquid can also be used and pumped continuously with a micropump until the patient’s seizures are controlled, and severe patients need to be sent to the ICU for treatment. The patient’s blood biochemistry should also be checked to find out the specific cause of the seizures and to treat the different causes. Only when the cause is removed can the epilepsy be controlled.