HPV vaccination is necessary for women at the age of 43, and the bivalent HPV vaccine is currently appropriate for that age. HPV vaccine, also known as human papillomavirus vaccine, can prevent certain subtypes of human papillomavirus from infecting the body after vaccination, and it is recommended for women of the right age to be vaccinated. The age suitable for bivalent HPV vaccine is 9~45 years old, and the main preventive range is HPV type 16 and HPV type 18. 43 years old women are still in the high-risk period of HPV infection, so it is considered necessary to receive HPV vaccine. At present, 43-year-old women in China can go to the vaccination point to make an appointment to receive the bivalent HPV vaccine, and after vaccination, they can obtain better preventive health effects.