Adverse effects of Dexamethasone Sodium Phosphate Injection include weight gain, acne, lower extremity swelling, muscle weakness, and nausea, as well as psychiatric symptoms such as agitation and delirium. Dexamethasone sodium phosphate injection is an adrenal hormone analog. Pharmacologically, adverse reactions to Dexamethasone Sodium Phosphate Injection often occur at pharmacologic doses, and in general, common adverse reactions include weight gain, acne, lower extremity swelling, muscle weakness, and menstrual disorders, as well as gastrointestinal disturbances such as nausea and vomiting. In addition to this, some patients may also experience psychiatric symptoms such as agitation, delirium, restlessness, and disorientation after using the drug. Secondly, there is also the possibility of serious adverse reactions such as ischemic osteonecrosis, osteoporosis, and easy bleeding tendency. Dexamethasone sodium phosphate injection can be used clinically for the treatment of connective tissue disease, rheumatoid arthritis, severe bronchial asthma and other diseases. The drug is generally contraindicated for people suffering from hypertension, thrombosis, gastric and duodenal ulcers, psychiatric disorders, electrolyte metabolism abnormalities, myocardial infarction, visceral surgery, glaucoma, and other diseases. To summarize, patients must use the drug under the guidance of a doctor, do not use dexamethasone sodium phosphate injection on your own, so as not to delay the condition and adversely affect your health.