There is no standardized regulation on what probiotics need to be supplemented after quadruple therapy, and it needs to be determined according to the actual situation of the patient. Currently, commonly used probiotics include lactobacillus, gram-positive bacteria, bifidobacteria, and so on. Quadruple therapy is mainly for the eradication of Helicobacter pylori, and this method includes 2 antibiotics, 1 bismuth agent, and 1 proton pump inhibitor, such as amoxicillin, furazolidone, bismuth pectin, and omeprazole, and this kind of drugs may affect the beneficial bacteria in the gastrointestinal tract while eradicating the Helicobacter pylori bacteria, which will result in an imbalance of the intestinal flora, and in this case, you can take lactobacillus, bifidobacterium, and other probiotics to This can be done by taking probiotics such as Lactobacillus and Bifidobacterium to regulate the stomach. Helicobacter pylori is the main cause of many kinds of gastritis, gastric and duodenal ulcers. Enterococcus faecalis among gram-positive bacteria can form biofilm in intestinal epithelium and play the role of protecting the intestinal epithelium; Bacillus cereus has a certain role in inhibiting bacteria and controlling infections, and the patients can also supplement the gram-positive bacteria after the quadruple therapy. Specifically what probiotics to supplement, patients can follow the guidance of professional doctors.