Tuberculosis for more than ten years without treatment may be self-healing or lead to the proliferation of the nucleus, it is recommended to diagnose tuberculosis and consult a doctor in time, active treatment. 1. Self-healing: For some patients with strong immune system and weak virulence of Mycobacterium tuberculosis, even if they have not been treated for more than ten years, the number of Mycobacterium tuberculosis will gradually decrease under the protection of their own immune system and they will gradually recover from the disease. 2. Tuberculosis proliferation: for most patients, ten years of untreated tuberculosis will lead to the continuous replication of Mycobacterium tuberculosis in the body, not only lung lesions aggravate, but also lesions outside the lungs, leading to the emergence of other symptoms. Tuberculosis untreated for more than ten years may be self-cured or lead to the spread of nuclei, but it is still recommended that patients should be actively treated under the guidance of the doctor after diagnosis, and standardized anti-tuberculosis treatment as soon as possible, to avoid aggravation of the condition or unnecessary or even irreversible damage to the lungs and other organs.