For patients with coronary artery disease who feel weakness in their limbs, it is usually due to the following factors. The common cause is the narrowing or occlusion of coronary artery lumen, which leads to insufficient blood supply and oxygen supply to the myocardium, and then there will be insufficient perfusion to the limbs. 2. If coronary heart disease causes arrhythmias, such as premature beats or atrial fibrillation, there will be symptoms of weakness in the limbs. 4.