H. pylori quadruple therapy, that is, patients need to take a bismuth agent, two antibiotics, and a proton pump inhibitor, the use of the course of 10 to 14 days. In performing H. pylori eradication therapy, patients can choose bismuth agents such as bismuth pectin and bismuth potassium citrate, commonly used proton pump inhibitors include omeprazole, lansoprazole, pantoprazole, etc., and antibiotics can be chosen from two of amoxicillin, clarithromycin, tetracycline, metronidazole and furazolidone. At the end of a course of treatment with quadruple therapy, patients should be reviewed after 4 to check the effectiveness of the patient’s H. pylori eradication treatment. If the patient develops H. pylori infection, please go to the hospital in time and follow the doctor’s instructions for medication.