The common causes of dry and flaky skin include physiological factors and pathological factors, and the pathological factors include contact dermatitis, ichthyosis and psoriasis. 1. Physiological factors: Generally in the fall and winter seasons, the weather is dry, do not pay attention to skin moisturizing, easy to lead to dry skin flakes. 2. Contact dermatitis: This disease is caused by skin contact with exogenous disease-causing substances, such as alcohol, bleach, strong acid, strong alkali, animal toxins, etc., which irritate the skin or trigger an allergic reaction. Long-term repeated exposure to these substances, the skin will appear scaly, cracked and mossy skin, epidermal peeling and other symptoms. 3. Ichthyosis: this disease is mainly caused by genetic factors, systemic diseases, drug factors, etc., manifested as dry skin, roughness, thickening and accompanied by ichthyoscale flaking and other symptoms. 4. Psoriasis: the cause of this disease is unknown, may be related to immune factors, genetic factors. It is characterized by red patches of skin, accompanied by dryness and flaking. It is recommended that the patient according to their own situation, if necessary, to the regular hospital dermatology department, follow the doctor’s instructions for a clear diagnosis, reasonable treatment.