Local skin bites by bedbugs appear red, swollen and itchy, generally belong to the insect bite dermatitis, mainly due to insect bites injected into the skin saliva may lead to local skin allergy and inflammatory reactions, treatment drugs usually include topical and internal two: 1, topical drugs: for redness, swelling, itching and other mild symptoms of patients can use glucocorticoid cream to apply, but also locally applied with anti-inflammatory, anti-itch Drugs with anti-inflammatory and anti-itch effects can also be applied topically. Commonly used drugs include dinaide cream, trimethoprim econazole cream, halometasone cream, butyl flufenamic acid ointment, etc. Furfuryl glycolate lotion can also be used for local rubbing to promote anti-itching. If accompanied by infection, fever, pus and other symptoms, you can apply local antibiotic cream, such as erythromycin ointment, tetracycline ointment, etc. to control infection; 2. Internal medications: antihistamines have anti-allergic effects, which are beneficial to promote rapid regression of skin inflammation, commonly used including benadryl, loratadine, cetirizine, etc. Patients with infections can be controlled with oral antibiotics, such as penicillin and cephalosporin. For patients with widespread lesions and severe allergic reactions, oral glucocorticoids such as prednisone and dexamethasone can be administered, but it is important not to take them for a long time. In addition, patients with bedbug bites should pay attention to keeping the local skin clean and dry, cut nails and wash hands regularly, avoid scratching and rubbing to avoid injury and infection. Strictly follow the doctor’s instructions and report any discomfort to the doctor in the process of medication.