MMR proteins are proteins encoded by the MMR gene, which have the functions of maintaining genome stability and reducing the rate of gene mutation, etc. MMR stands for mismatch repair. MMR is the abbreviation of English mismatch repair, mismatch repair is mismatch repair. MMR gene is a kind of conserved gene in biological evolution, belongs to the housekeeping gene (a kind of genes expressed by all cells, whose products are necessary for maintaining the basic cellular life activities), and it has the function of repairing the mismatch of base in the process of DNA replication, which is helpful for maintaining the high fidelity of DNA replication. high fidelity of DNA replication. Loss of control of the MMR gene results in a loss of expression of the functional protein it encodes, MMR protein, which affects the normal replication of DNA and alters normal cellular function, thereby causing tumors.MMR defects have been associated with a variety of tumors, such as hereditary nonpolyposis colorectal cancers, and some sporadic colorectal cancers, among others. Please consult your physician for specific information, and the cause of the disease and standardized treatment should be clarified under the guidance of your physician.