Whether total bilirubin 26.2μmol/L is serious or not needs to be judged according to the patient’s specific situation. Usually, the normal reference range of serum total bilirubin is 5.13-22.24 μmol/L, while 26.2 μmol/L is out of the normal range, which is a situation of elevated total bilirubin. Elevated total bilirubin may be due to physiologic increase triggered by long-term alcohol consumption, strenuous exercise, neonatal factors, etc., which is not serious in this case. However, pathological elevation caused by neonatal pathological jaundice, hepatitis, cirrhosis, cholelithiasis, obstructive jaundice, hemolytic jaundice, pancreatic head cancer, etc. is more serious. The specific degree of severity should be judged according to the degree of the patient’s condition, and the patient should take systematic standardized treatment according to the cause of the disease in time. It is recommended that if the total bilirubin is 26.2μmol/L, the severity should be judged according to the patient’s specific condition.