Anesthetic drugs broadly include local anesthetics and general anesthetics, whose mechanism of action is reversible blockade of the body’s peripheral nerves and affect the central nervous system, so as to achieve pain relief, sedation or and loss of consciousness, which plays a very important role in surgical treatment. These side effects and performance of anesthetic drugs may occur: 1, anesthetic allergy: all anesthetic drugs have the possibility of allergy, but the incidence is low, and individual differences are large, mostly manifested as hives, severe cases can be manifested as laryngeal edema, airway spasm, blood pressure drop, etc.; 2, nausea and vomiting and reflux aspiration: patients with nausea and vomiting, to promptly clean up the vomit to prevent aspiration of the airway. If the vomit cannot be cleared in time or regurgitation of gastric contents caused by various reasons, it may lead to aspiration of gastric contents into the lungs, which is called misaspiration. Patients will experience choking and coughing, respiratory distress, asphyxia, hypoxia, which can cause aspiration pneumonia and even endanger life; 3. Hyperventilation: it can cause changes in respiratory amplitude and frequency, mostly manifested as weakening and decreasing, feeling chest tightness and shortness of breath, wheezing, and in severe cases, patients will experience 4, blood pressure changes, heart rhythm abnormalities: patients appear too high or too low blood pressure, feel panic and shortness of breath, dizziness, palpitations and other symptoms; 5, delayed awakening: patients may have delayed awakening time, especially patients of advanced age and with systemic metabolic diseases; 6, postoperative delirium: a small number of patients appear transient perceptual disorders after anesthesia, showing agitation, hallucinations and dreams appear, not fully cooperative mental state, for safety reasons can require family members to accompany, to avoid accidents; 7, malignant hyperthermia: very rare complications of anesthesia, related to genetics, mostly after the application of inhalation anesthesia and other anesthetic drugs, patients will appear high fever, convulsions, convulsions and other neurological symptoms; appear a sharp rise in body temperature, even higher than 42 ℃, high mortality. It is important to detect resuscitation in time, and early intravenous injection of the potent drug dantrolene is one of the most effective methods to reduce mortality.