Roxithromycin and alcohol, there is not necessarily an allergic reaction, and alcohol allergic reaction of the drug, the most common is the cephalosporin, mixed with alcohol to produce a certain drug reaction, called disulfiram-like reaction, at this time, there will be itching of the skin around the body, the severe cases will be anaphylactic shock. However, roxithromycin and alcohol will produce a certain pharmacokinetics, and pharmacokinetics reduced chemical reaction, for roxithromycin is not allergic to the person, drinking alcohol may appear secondary allergy, or not allergic to alcohol, taking roxithromycin immediately after drinking alcohol, there will be symptoms of alcohol allergy. Because roxithromycin belongs to the class of macrolides, macrolides and alcohol together, will reduce the active ingredients of the drug and drug concentration, so roxithromycin should not drink alcohol after taking.