There is no aceclofenac and diclofenac which is better, these two belong to the same non-steroidal anti-inflammatory drugs, the specific effect of which is better with the patient’s own condition and sensitivity to the drug, it is recommended to follow the doctor’s instructions to use the drug. Aceclofenac can be used to treat symptoms of pain and inflammation caused by osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. Diclofenac, or diclofenac sodium, can be used for acute joint inflammation and gouty attacks, chronic joint inflammation, rheumatoid arthritis, and swelling or inflammation after trauma or surgery. Common adverse reactions to the use of the drug include indigestion, abdominal pain, nausea and diarrhea. It is contraindicated in patients who are allergic to the product, patients with asthma, urticaria or allergic reactions induced after aspirin or other NSAIDs, patients with a history of gastrointestinal bleeding or perforation after NSAIDs, patients with active peptic ulcers/bleeding, and patients with heart failure. Avoid coadministration with other NSAIDs, including selective COX-2 inhibitors. Adverse effects can be minimized by using the lowest effective dose for the shortest duration of therapy, as needed for symptom control. Aceclofenac and diclofenac are both NSAIDs, and which one is more effective depends on the patient’s own condition and sensitivity to the drug. Patients are advised to use the medication correctly under the guidance of a doctor, and not to change the dosage of the medication without authorization or abuse the medication privately.