The pain reflex zones of heart disease are mainly concentrated in the precordial region, but can also radiate to the left shoulder and left upper extremity, as well as the back. 1. Anterior heart region: Heart disease is now a common condition, mostly seen in middle-aged and elderly people. Symptoms of heart disease usually include palpitations (rapid heartbeat, often accompanied by panic), fatigue, shortness of breath and other discomforts, or produce symptoms such as dyspnea, shortness of breath, fatigue, and blue lips. When the patient has an attack of the disease, the main manifestation is a painful sensation in the anterior region of the heart. 2. Left shoulder and left upper limb: the pain reflex zone of heart disease can radiate to the left shoulder and left upper limb is because the pain fibers in the central nervous system has a common pathway, the left shoulder and left upper limb and the heart is subject to the same section of the spinal nerve innervation, which leads to some patients in the pain of the heart disease will think that he or she is myofascial or cervical spondylosis problems, while ignoring the examination of the heart, leading to irreversible damage. 3. Back: there are some patients with heart pain reflex zone in the back, because the human visceral nerve, is not a very accurate positioning of the nerve, once there is heart pain will be dispersed to the back, but also therefore heart attack pain will be easily mistaken for orthopedic diseases, and affect the diagnosis of heart disease. Therefore, if you have difficulty breathing but are not wheezing, you should have an electrocardiogram (ECG) and chest X-ray to rule out heart disease. Chest radiographs, electrocardiograms, echocardiograms, blood biochemistry and other tests, as well as pulmonary function to determine lung disease.