Bitter mouth, tastelessness and fatigue can be solved by general treatment with medication. Drugs such as gentian diarrhea liver pill, ginseng and atractylodes, etc.. 1. General treatment: usually pay attention to not stay up late, ensure emotional peace, not angry and fire, in order to protect the liver and gallbladder; regular diet, light, avoid spicy stimulation, greasy and cold food, solid protection of the spleen and stomach function, to avoid the long lead to the spleen and stomach cold (spleen and stomach weakness and cold). 2. Medication: Bitterness, tastelessness and fatigue are generally caused by heat in the liver, gallbladder and stomach, or deficiency of spleen and stomach qi. For bitter mouth caused by liver and gallbladder fire, you can take Longdian Diarrhea Liver Pill to regulate it; for stomach fire, you can take Qingtu San to regulate it; and for spleen and stomach qi deficiency, you can take Sijunzi Soup or Ginseng Ling Baijushu San to benefit qi and strengthen the spleen (to regulate the qi of the spleen and stomach). Bitter mouth, tastelessness and fatigue should be treated by professional doctors.