Colon cancer is one of the common malignant tumors. Late stage symptoms of colon cancer often include jaundice, ascites, swelling and other signs of liver metastasis, as well as cachexia, anterior rectal concave mass, enlarged supraclavicular lymph nodes and other signs of distant tumor spread and metastasis. The clinical manifestations of late stage colon cancer may vary according to the location of cancer. So what are the treatment methods of late stage colon cancer? 1.Arterial chemotherapy is the main chemotherapy for advanced colon cancer, which can shrink the cancer to a certain extent, but it will increase the toxic side effects with the prolongation of treatment time, therefore, chemotherapy drugs and chemotherapy time should be based on tumor remission, symptom relief and treatment-related toxicity. 2.Radiotherapy is also one of the more clinically used treatments for colon cancer in late stage, which can shrink the tumor and improve the symptoms, and usually combined with chemotherapy, the effect is better than radiotherapy or chemotherapy alone. However, radiotherapy is more harmful to the body and should be used with caution for patients with poor physical function in advanced colon cancer. In addition, in view of the toxic side effects of radiotherapy and chemotherapy on human body, Chinese medicine can be combined in the treatment of advanced colon cancer to enhance the effect and reduce the toxicity. Although the short-term effect is not as obvious as chemotherapy, the long-term effect is good, and it has obvious role in improving the quality of survival and prolonging the survival period. 4.Patients with advanced colon cancer should also pay attention to daily dietary regimen, good body function and strong immunity can resist the development of cancer and tolerate various drug treatments. Therefore, it is extremely important for patients with advanced colon cancer to improve immune function and enhance resistance to tumor.