Aspirin is effective for atherosclerosis, aspirin belongs to the anti-platelet drugs, for the prevention of atherosclerotic plaque and thrombosis, is a certain role. Aspirin can be antiplatelet, antithrombotic, able to prevent atherosclerotic plaque rupture thrombosis, thereby reducing the probability of patients with cardiovascular and cerebrovascular disease, often as a secondary prevention of atherosclerosis, in addition to the routine use of lipid-lowering statin drugs, such as atorvastatin, reserpinevastatin and so on. In daily life, low-salt and low-fat diet, smoking and alcohol cessation, and moderate exercise are needed. Patients with thrombocytopenia or peptic ulcers should be cautious to disable aspirin. Adverse effects of aspirin may cause gastrointestinal bleeding, occasional nausea and vomiting, possible allergic reactions in patients with asthma, rare hepatic and renal dysfunction, and possible dizziness and tinnitus in the elderly. It is recommended that the medication be used in accordance with medical advice, and when any of these adverse reactions occur, the medication should be discontinued immediately and medical attention sought so that the physician can make a judgment and take the necessary therapeutic measures.