There is a possibility of cure for stage I nephropathy, but whether it can be cured or not depends on the cause of the disease and renal pathology of the patient. The characteristics of stage I nephropathy mainly include glomerular filtration rate is generally ≥90mL/min, at this time, the prevention and treatment goals and measures are generally timely diagnosis of the cause of the disease, relief of symptoms, protection of renal function, and delay the continued progression of nephropathy. The more normal glomeruli the patient has, the less renal function is impaired, and there is a greater chance that the patient can return to normal. However, whether it can be cured or not depends on whether the patient suffers from hypertension, proteinuria, smoking, anemia, hyperlipidemia, hyperhomocysteinemia and malnutrition and other risk factors, these risk factors are not cured, the patient’s renal failure will be gradually progressive, which is not conducive to the patient’s recovery. Patients with Stage I Nephropathy must strictly follow the doctor’s instructions for treatment and must not change the treatment plan without authorization.