For the second recurrence of cerebral thrombosis, the patient should be given active treatment in the acute phase, and the patient’s blood condition should be checked. If the patient has hyperfibrinogenemia, the patient can be given the intravenous application of bacitracin. If the patient has thrombocytosis, the patient can also be given anti-platelet aggregation treatment, such as oral aspirin or intravenous ozagrel sodium. The second recurrence of cerebral thrombosis, to give the patient to activate blood circulation and remove blood stasis of drugs, commonly used in the clinic are shuxu haeming injection, injection of thromboxane, and vincristine and other drugs, can be given to the patient to apply scavenging oxygen free radicals, cerebral protection of drugs, commonly used in the clinic are edaravone injection, butylphthalide injection. After acute treatment, if the patient’s condition is stabilized, rehabilitation treatment can also be carried out. It is recommended that the patient should carry out systematic rehabilitation treatment, and at the same time, the secondary prevention of cerebrovascular should be actively initiated to prevent the recurrence of cerebral thrombosis.