Precardiac disease often has the following signs and symptoms: 1. Heart murmur: It is the most common sign of precardiac disease, and most precardiac disease will have a heart murmur. If a newborn is born with a heart murmur, an echocardiogram should be done to find out if a heart malformation is present. At any age, whenever a heart murmur is detected, an echocardiogram should be performed to confirm the diagnosis. Heart murmurs are most often heard in common conditions such as ventricular septal defects, pulmonary stenosis, aortic stenosis, patent ductus arteriosus, and atrial septal defects, while most other complex malformations also have heart murmurs. It is important to note that not all precordial disease can be heard, and some very complex, severe precordial disease may not be heard. There are also some people who hear murmurs but do not have precordial disease, called “functional murmurs” or “physiological murmurs”. 2, cyanosis: that is, cyanosis, is usually said that the patient looks blue and purple, mainly in the mouth and lips, finger (toe) nails, skin cyanosis, crying aggravated. This is often a sign of complex preconditioning. If a newborn is born with cyanosis, the majority of them will have complex preconditioning. The common ones are complete transposition of the great arteries, pulmonary atresia, tricuspid atresia, and complete ectopic drainage of the pulmonary veins. The gradual appearance of cyanosis after 3 months of life is commonly associated with tetralogy of Fallot. 3.Shortness of breath and labored breathing: mostly occur in cyanotic precordial disease, caused by hypoxia. 4, like “squatting”: “squatting” means squatting position, and patients with tetralogy of Fallot often like to make “squatting” position, which can relieve the feeling of shortness of breath and effort. 5, hypoxic episodes: cyanotic preconditioning patients due to severe hypoxia will appear syncope, unconscious, mostly in the effort, crying episodes, common in tetralogy of fallot. 6, repeated respiratory infections, pneumonia: common in more severe ventricular septal defect, arteriovenous catheterization, atrial septal defect ventricular defect and other complex malformations. 7, malnutrition, stunted development: infants with severe precordial disease often have difficulty feeding and slow weight gain. Mostly manifested as fast breathing, sweating, hoarse cry, with chicken chest. It is mostly seen in the combination of pulmonary hypertension of precordial disease. Parents, if you find that your child has the above symptoms, please take your child to the hospital in time for consultation. If you have simple questions for consultation before consultation, please leave a message online, if you need in-depth communication, please choose telephone consultation.