Tongue root contour papillae hyperplasia need to be targeted medication, for vitamin deficiencies, need to supplement multivitamins, anemia needs to be corrected when anemia, the emergence of inflammation using antibiotics. 1. Vitamin deficiency: the contour papilla is located in the posterior third of the tongue, hyperplasia can be seen in malnutrition vitamin deficiency, it is recommended to supplement multivitamins. 2. Anemia: contour papillae hyperplasia can also be seen in anemia caused by oral iron, folic acid or vitamin B₁₂. 3. External factors stimulation: external food, drug stimulation of local inflammation can gargle chlorhexidine or oral amoxicillin. Tongue root contour papillary hyperplasia, it is recommended to the hospital to check the causes of hyperplasia, remove the external bad restorative body, eat less stimulating food, follow the doctor’s instructions on the cause of the medication, the use of drugs is strictly prohibited during the consumption of alcohol, the elderly, pregnant women, children are recommended to consult a physician before using the drug. Drugs should be used under the guidance of a physician.