Low-grade glioma is the most common malignant tumor in the skull, and surgical resection is clinically preferred to prolong the survival of patients. Surgical resection of tumors can reduce intracranial pressure and relieve the symptoms of tumor compression on brain nerves. Adequate cerebral decompression must be obtained for resection of low-grade glioma to create opportunities for later radiotherapy and chemotherapy. The combination of local radiation therapy is needed after surgery, which can significantly prolong the survival of patients. The current commonly used chemotherapy drug is temozolomide, which can be used alone. For patients with tumor recurrence, a 2nd surgery can be considered. The overall survival of patients with low-grade glioma is around 5-10 years.