High leukocytes detected in urine sediment examination may be caused by pyelonephritis, vaginitis, renal tuberculosis, interstitial nephritis and other reasons. 1. Pyelonephritis: Pyelonephritis can be induced when the kidney area is attacked by microorganisms, and elevated leukocytes can be seen in the urine sediment test, which is often accompanied by fever, lumbago, hematuria and other clinical symptoms. 2. Vaginitis: vaginitis can be induced when the vaginal area is infected by bacteria, and the stimulation of inflammation can lead to high leukocytes in urine sediment. 3. Kidney tuberculosis: Kidney tuberculosis can be induced by Mycobacterium tuberculosis infection in the kidney area, and high leukocytes in the urine sediment may appear, which may be combined with fever, night sweating (sweating abnormally after going to sleep, and sweating stops after waking up), frequent urination, urgency of urination and other symptoms. 4. Interstitial nephritis: aseptic pyuria is often seen, that is, the urine sediment leukocytes are positive, no bacterial growth in urine culture, and there is no discomfort in urination, and may be combined with proteinuria, hypospadias, diabetes mellitus and so on. There are many other causes of high urine sediment leukocytes, such as cystitis or prostatitis. It is recommended that patients with positive urine sediment leukocytes, timely regular hospitals, under the guidance of the physician to improve the relevant examination, a clear diagnosis, targeted treatment.