The main reasons for persistent non-stop menstruation are: i. Pregnancy-related, commonly including miscarriage, ectopic pregnancy, and gravidity. Second, ovarian endocrine dysfunction, mainly including anovulatory type dysfunctional uterine bleeding and ovulatory menstrual disorders. In addition, a brief decrease in estrogen level can also lead to continuous uterine bleeding. Third, genital tumors. Uterine fibroids are common benign tumors that cause persistent vaginal bleeding. Ovarian tumors that secrete estrogen can also cause persistent irregular vaginal bleeding. Almost all other tumors are malignant, including vaginal cancer, cervical cancer, endometrial cancer, gestational trophoblastic tumors, and fallopian tube cancer. Fourth, others, including those related to systemic diseases such as combined thrombocytopenic purpura, aplastic anemia and leukemia during pregnancy.