Whether a crooked mouth is facial paralysis or stroke is determined by the patient’s symptoms and the results of auxiliary examinations. If the patient has a crooked mouth, a skewed face, and weakness in opening and closing the eyes, it may be peripheral facial paralysis caused by idiopathic facial neuritis, and it is necessary to go to the hospital in time. It is recommended to confirm the diagnosis by neurography and electromyography, and the diagnosis can be confirmed by using dexamethasone, prednisone, and other medicines under the instruction of the doctor. Patients with crooked mouth, accompanied by dizziness, vomiting, blurred vision, slurred speech and hemiplegia (one side of the limbs can not move freely) and other symptoms, we should consider whether there is the possibility of stroke, the majority of stroke patients are elderly people, so we should pay attention to the physical condition of the elderly, and once found to be in a timely manner to seek medical treatment, to avoid serious consequences, it is recommended to improve the cranial brain magnetic resonance examination, to clarify the cause of the disease, and actively treat the disease. It is recommended to improve the cranial MRI examination to clarify the cause of the disease and actively treat it. Regardless of whether the crooked mouth is facial paralysis or stroke, when patients have symptoms of crooked mouth, they should go to the hospital in a timely manner, to clarify the cause of the disease, and standardized treatment under the guidance of the doctor.