The baby does not runny nose does not cough for no reason fever, need to be based on the cause of treatment; if due to infectious factors, can be applied under the guidance of the physician anti-infective drugs to treat; if due to non-infectious factors, need to be directed at the cause of the treatment. 1. Infectious factors: the baby does not have a runny nose, not coughing fever for no reason, and there is no clinical manifestations, need to be alert to the possibility of hidden infections, can be temporarily to the physical cooling, if necessary, add ibuprofen antipyretic. And according to the physician to assess the baby’s situation, if conditions permit, can be hospitalized to improve the urine routine, cerebrospinal fluid and other tests, alert to urinary tract infection and intracranial infection. If consider urinary tract infection, can complete urine culture, and according to the results of the culture to follow the doctor to be amoxicillin and other anti-infective treatment, if consider purulent meningitis can follow the doctor to be meropenem and other anti-infective treatment. 2. non-infectious factors: for example, the baby suffers from leukemia, heat stroke, Kawasaki disease, juvenile idiopathic arthritis and other diseases can lead to fever. In this case, it is also recommended to be hospitalized to improve the relevant examination, treatment can be temporarily to physical cooling, ibuprofen, rehydration and other symptomatic supportive treatment. After a clear diagnosis, according to the cause of the targeted treatment. The baby does not runny nose does not cough for no reason fever, need to go to the hospital to diagnose the cause of treatment, they can not randomly use drugs.