Toothpaste generally does not cause oral cancer, and each person’s daily use of toothpaste is limited, in addition to the need to rinse your mouth with water after each brushing, which will also effectively reduce the residue of toothpaste in the mouth. Toothpaste mainly contains friction agents, foaming agents, moisturizers, etc., no carcinogenic substances. The amount of toothpaste used and the contact time with the mouth are short, so it will not lead to oral cancer. It is important to note that toothpaste containing antibacterial ingredients should not be used for a long period of time. Prolonged use of toothpaste containing antibacterial ingredients will destroy the normal flora in the oral cavity while inhibiting and killing pathogenic bacteria, thus destroying the “ecological balance” of microorganisms in the oral cavity and causing new oral diseases.