Premature ejaculation is a disease with the highest incidence of male sexual dysfunction, due to premature ejaculation makes ejaculation too fast, so that the quality of male sexual life is not satisfied. Premature ejaculation is defined as the concept of premature ejaculation when a man has poor control of ejaculation after insertion of the male penis into the woman’s vagina during sex for a period of less than 2 minutes and for a duration of 6 months or more. Often many early patients may be more severe, some may ejaculate just after the penis touches the woman’s skin, or in some cases just after erection. Treatment for premature ejaculation is needed to improve symptoms and return men to normal sexual function. Commonly used treatments for premature ejaculation include medication, commonly used drugs such as dapoxetine and sertraline for oral treatment of premature ejaculation. In addition, it can also be prolonged by topical medications, such as lidocaine cream applied to the glans to reduce glans sensitivity.