The severity of the condition cannot be stated solely on the basis of a serum homocysteine of 50 μmol/L, but also needs to be evaluated in the context of the patient’s past history, such as the presence or absence of diabetes mellitus, cardiac disease, and hypertensive disorders. Homocysteine is an intermediate metabolite resulting from the conversion of the essential amino acid methionine to cysteine, a reactive vascular damage amino acid. Normal human fasting plasma homocysteine concentration is 5 -15 μmol/L. Homocysteine is also a risk factor for many diseases such as atherosclerosis, heart disease and stroke. Therefore, in order to prevent homocysteine elevation at an early stage, we should stop smoking, stop drinking, strengthen exercise and control body weight; in terms of dietary prevention, we can increase the intake of fruits and vegetables, reduce the intake of high-fat and high-calorie foods, and also supplement folic acid, vitamin B6 and vitamin B12. If homocysteine is elevated, it is necessary to consult a doctor in time to identify the cause and actively cooperate with the doctor’s treatment.