It is generally normal to have no pregnancy reaction on the 50th day of pregnancy because everyone has a different body type, resulting in different sensitivity to pregnancy hormones, and some may have early pregnancy reactions, while others may have no early pregnancy reactions. After pregnancy, most women start to experience pregnancy vomiting around 40 days after menopause due to the rapid increase of estrogen level and human chorionic gonadotropin level in the body. The high estrogen level will stimulate the gastrointestinal tract, causing smooth muscle spasms in the gastrointestinal tract, resulting in nausea and vomiting. Some pregnant women may be more sensitive and experience vomiting in the first month of pregnancy, while others may experience vomiting later or even not at all. The absence of pregnancy vomiting on the 50th day of pregnancy can also be seen in some special cases, such as ectopic pregnancy and fetal abortion. If this is accompanied by vaginal bleeding, abdominal pain and other abnormalities, it is recommended to go to the obstetrics and gynecology department of the hospital in time to improve the relevant auxiliary examinations to clarify the fetal condition.