The best time for minimally invasive surgery for uterine fibroids is recommended to be within 3-7 days of menstrual cleansing, and do not have coitus, and to do routine leukorrhea test before the surgery, mainly to exclude inflammation of the vagina. If there is inflammation of the vagina, it is recommended to cure it before surgery. In addition, during this period of time, the pelvic congestion has been completely relieved, and intraoperative bleeding will be relatively reduced. For patients with submucous fibroids causing heavy bleeding, it is recommended to have surgery as soon as possible to treat the problem. If there is a lot of bleeding, it will cause the patient’s state of anemia and even threaten the safety of life. Therefore, the choice of time for surgery varies from case to case. Before doing minimally invasive surgery for uterine fibroids, it is better to draw blood to check the three items of gynecological oncology to exclude the possibility of malignant changes of fibroids.