A systolic blood pressure of 180 mmHg is relatively severe, and the assessment of their risk of cardiovascular and cerebrovascular events is also based on a combination of risk stratification based on the presence of risk factors, target organ damage, and clinical disease. Common cardiovascular risk factors included men >55 years of age and women >65 years of age; smoking; impaired glucose tolerance; dyslipidemia; family history of early-onset cardiovascular disease; and abdominal obesity. Target organ damage was mainly reflected in left ventricular hypertrophy, carotid ultrasound showing intramedullary thickness ≥0.9 mm or atheromatous plaque in the strong arteries, and carotid-femoral pulse wave velocity ≥12 m/s. Clinical diseases included cerebrovascular diseases such as cerebral hemorrhage and ischemic stroke; cardiac diseases such as angina pectoris and history of myocardial infarction; renal diseases such as impaired renal function and diabetic nephropathy; peripheral vascular diseases; retinopathy such as optic papillae edema with hemorrhage or oozing; and diabetes mellitus. A systolic blood pressure of 180 mmHg is classified as grade 3 hypertension on the blood pressure scale, and the risk stratification is high-risk if there are no other risk factors or medical history, and very high-risk if there are other risk factors in combination or if there is target organ damage and clinical complications. People with high or very high risk should seek medical attention in a timely manner, and once diagnosed, they should undergo comprehensive treatment for hypertension and its coexisting risk factors and clinical conditions under the guidance of a physician, in order to control their blood pressure, minimize target organ damage, and prevent complications.