Deep lines can be improved by hyaluronic acid fillers, botulinum toxin injections, photoelectric treatments and surgical treatments. The lines are caused by the sagging of skin and subcutaneous tissues in the mid-face, and the shrinkage of subcutaneous fat, which will make people look particularly old and affect the beauty of the face. 1. Hyaluronic acid filler: Hyaluronic acid is injected as a filler material into the sunken area of the lines, which can better support the skin and improve the lines, and at the same time, it can also play the effect of hydration and moisturizing. 2. Botulinum toxin injection: Botulinum toxin is injected into the area with worry lines, which can inhibit the muscle contraction by blocking the information transmission between the nerve and the muscle, so as to achieve the effect of lightening and removing worry lines. Since muscle contraction is not the main cause of the lines, botulinum toxin injection is generally only used as an adjunctive treatment in clinics. 3. Photoelectric treatment: radio frequency, ultrasonic knife and Thermage can activate the skin fibers through the heat generated by electromagnetic wave, which can tighten the skin, anti-wrinkle effect, and improve the appearance of lines. 4. Surgery: For those who are not satisfied with the above measures or those who are in pursuit of long-term effects, surgery can be considered. Currently, common clinical procedures to improve the appearance of wrinkles include: autologous fat transplantation, micro-latissez-faire, and lower facial wrinkle removal. As the above treatments require high professional skills, it is recommended that patients in need of such treatments should visit regular medical institutions and choose the appropriate improvement methods under the guidance of doctors.