Yunnan Baiyao is mostly used for bruises and injuries and has no clear therapeutic effect on tendon sheath cysts. Tendon sheath cysts are cystic swellings that occur in the tendon sheaths, mostly on the back of the wrist and the back of the foot, caused by local injuries and chronic strain. Yunnan Baiyao has the efficacy of resolving blood stasis and stopping bleeding, activating blood circulation and relieving pain, and it is mainly used for treating bruises, vomiting blood, blood in stool and other diseases. There is no obvious indication for tendon sheath cysts. For the treatment of tendon sheath cysts, smaller asymptomatic tendon sheath cysts are mainly observed, and can sometimes be absorbed on their own. If the cyst is large and symptoms such as nerve entrapment occur, it can be treated with puncture and aspiration, injection of anti-inflammatory glucocorticoid drugs such as prednisolone acetate, and surgery. After the diagnosis of tendon sheath cysts, if the cysts are large and painful, it is recommended to consult a doctor and follow the doctor’s instructions. The use of medications should be in accordance with the doctor’s instructions.